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2003 | 57 | 1 | 33-53
Article title

Biological activities of lipopolysaccharide

Title variants
Languages of publication
PL
Abstracts
EN
Lipopolysaccharides (LPS, endotoxin) are known to be responsible for the initiation of endotoxic shock, therefore they can be targets for new preventive and therapeutic strategies. This review describes the biological and physicochemical properties of endotoxin ? major component of the outer membrane of Gram-negative bacteria. The paper focuses on response of the host to endotoxin, recent knowledge about the target cells and receptors for LPS, mechanisms of innate immune response and cell signal transduction due to the LPS recognition. It also summaries results of studies on LPS structure influence on its biological activity.
Publisher

Year
Volume
57
Issue
1
Pages
33-53
Physical description
Contributors
author
References
Document Type
ARTICLE
Publication order reference
J. Lukasziewicz, Instytut Immunologii i Terapii Doswiadczalnej PAN ul. R.Weigla 12, 53-114 Wroclaw, Poland
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YADDA identifier
bwmeta1.element.element-from-psjc-634bf618-870a-3acf-af53-981cb3242a94
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