Biological properties of lipoic acid
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Lipoic acid is a prostetic group of H-protein of the glycine cleavage system and the dihydrolipoamide acyltransferases (E2) of the pyruvate, alpha-ketoglutarate and branched-chain alpha-keto acid dehydrogenase complexes. Lipoic acid and its reduced form, dihydrolipoic acid, reacts with oxygen reactive species. This paper reviews the beneficial effects in oxidative stress models or clinical conditions.
Publication order reference
A. Bilska, Instytut Biochemii Lekarskiej CM UJ, ul. Kopernika 7, 31-034 Krakow, Poland