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2003 | 44 | 3 | 413-418
Article title

The influence of calyculin A on lymphocytes in vitro

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EN
Abstracts
EN
Human lymphocytes were cultured in vitro and treated with calyculin A. The aim of this work was to estimate the influence of calyculin A on chromosome morphology and banding patterns. It was also interesting whether calyculin A treatment is useful in cytogenetic analysis of human karyotype. We proved that calyculin A induces chromosome condensation in lymphocytes and raises the mitotic index significantly. Moreover, calyculin A does not influence the banding patterns. Therefore it is concluded that calyculin A can be clinically useful for human karyotyping.
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Year
Volume
44
Issue
3
Pages
413-418
Physical description
References
Document Type
SHORT COMMUNICA
Publication order reference
M. Srebniak, Department of Perinatology and Gynaecology, Silesian Medical Academy, Plac Traugutta 6, 41-800 Zabrze, Poland
YADDA identifier
bwmeta1.element.element-from-psjc-5ff91598-dc31-3ed4-9920-954fa0962292
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