Biomechanic shear stress in carotid arteries and atherosclerosis development

• Authors: R. Kazmierski
• Languages of publication: PL

Abstracts

EN

One of the major hemodynamic forces acting on blood vessels is shear stress, which is, the friction force between the endothelial cell surface and flowing blood. Arterial shear stress within physiologic range (15-70 dyne/cm2) induces endothelial quiescence and an atheroprotective gene expression profile. Low shear stress (< 4 dyne/cm2 ) stimulates atherogenic phenotype, whereas, high shear stress (>70 dyne/cm2 ) induce prothrombotic state.

Keywords

EN

ATHEROSCLEROSIS; CAROTID ARTERY; ENDOTHELIAL CELL; SHEAR STRESS; STROKE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2003
• Volume: 57
• Issue: 6
• Pages: 713-725

Contributors

author

R. Kazmierski

• Document Type: ARTICLE
• Publication order reference: R. Kazmierski, Katedra i Klinika Neurologii Akademii Medycznej, ul. S.Przybyszewskiego 49, 60-355 Poznan, Poland