Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl


Preferences help
enabled [disable] Abstract
Number of results
1993 | 53 | 1 | 15-23

Article title

Calcium signaling in the brain

Selected contents from this journal

Title variants

Languages of publication



Calcium ions regulate many processes in the central nervous system via interaction with intracellular calcium-binding proteins. One class of these proteins shares a common structural motif, the EF-hand. A consensus amino acid sequence for this motif has aided the identification of many new members of this family. Some of these proteins, like parvalbumin, calbindin, and calretinin, proved to be useful neuronal markers for a variety of functional brain systems and their circuitries. Their major role is assumed to be buffering, transport of Ca?+, and regulation of various enzyme systems. Cellular degeneration is often accompanied by Ca?+ overload. It has been assumed that neurons containing certain intracellular Ca?+ - binding proteins may have a greater capacity tu buffer Ca?+ and therefore would be more resistant to degeneration.



Document Type


Publication order reference


YADDA identifier

JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.