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1997 | 51 | 4 | 385-398
Article title

The role of genetic factors apoptosisi and 14-3-3 protein in the induction of some atopic diseases

Title variants
Languages of publication
PL
Abstracts
EN
In this review we try to summarize some of the new informations about the genetic base of bronchial asthma. We also mention apoptosis (programmed cell death) as the process modulating cell proliferation, differentiation and death. According to the latest reports, the disorders of the regulation of apoptosis may play an important role an the pathogenesis of autoimmunologic and atopic diseases (including bronchial asthma), AIDS and neoplasmatic diseases. There is a linkage between the induction of apoptosis and signal transduction disorders. We describe the Raf/MECK/ERK/MAP signal transduction pathway and 14-3-3 protein - the peptide which possibly might participate in the initiation of the programmed cell death.
Keywords
Year
Volume
51
Issue
4
Pages
385-398
Physical description
Contributors
author
author
author
author
References
Document Type
article
Publication order reference
E.Jagiello, Klinika Chorob Wewnetrznych i Alergologii AM, ul.Traugutta 57, 50-417 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-5cbfb2a8-d92a-3e9e-9f90-c34355d6ea3c
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