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2002 | 43 | 3 | 391-395
Article title

Monte Carlo simulation of genome viability with paralog replacement

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Languages of publication
EN
Abstracts
EN
Recent analyses of genome content have revealed that many single functions, even in haploid organisms, can be executed by more than one gene. As a result, experimental disruption of many individual genes does not exert lethal effects on the organism or even any visible change in the phenotype of the organism with a knockedout gene. Our analysis shows that such genetic redundancy allows for an appreciably higher mutation load in the genome simulations before the viability of the whole organism is destroyed.
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Publisher

Year
Volume
43
Issue
3
Pages
391-395
Physical description
Contributors
author
author
References
Document Type
ARTICLE
Publication order reference
S. Cebrat, Institute of Microbiology, Wroclaw University, ul. Przybyszewskiego 63/77, 51-148 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-591188cf-c9d6-30b2-923d-08243f7cfade
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