Recent discoveries in the genetics of melanoma and their therapeutic implications

• Authors: A. Marquette , M. Bagot , A. Bensussan , N. Dumaz
• Languages of publication: EN

Abstracts

EN

The incidence of cutaneous malignant melanoma, tumors arising from melanocytes, has increased markedly over the past few years in many countries. Although early melanoma is curable through surgical excision, the prognosis of advanced melanoma is very poor, this tumor being resistant to current therapies. Thus there is a need for new therapies to improve the treatment of advanced melanoma. This review provides an overview of recent discoveries in the genetics of melanoma which could offer new therapeutic opportunities.

Keywords

EN

MELANOMA; MOLECULE INHIBITOR; RECEPTOR; TYROSINE KINASE

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 2007
• Volume: 55
• Issue: 6
• Pages: 363-372

Contributors

author

A. Marquette

author

M. Bagot

author

A. Bensussan

author

N. Dumaz

• Document Type: REVIEW
• Publication order reference: Nicolas Dumaz, Faculte de Medecine de Creteil, INSERM U841, Equipe 02, 8 rue du General Sarrail, 94010 Creteil, France