Preferences help
enabled [disable] Abstract
Number of results
2003 | 51 | 3 | 195-200
Article title

Diagnostic value of pancreatic elastase-1 in human acute pancreatitis

Title variants
Languages of publication
The diagnosis of acute pancreatitis is usually confirmed by a significant increase of the serum amylase and/or lipase level. However, serum pancreatic elastase?1 (pEla-1) was found to be a more sensitive diagnostic marker in acute pancreatitis (AP), when assayed by RIA procedure. We analysed the serum concentration of pancreatic elastase-1, measured by ELISA technique in 46 patients with acute pancreatitis and in the control group of 12 healthy volunteers. At admission (day 1) we found significantly higher pEla-1 level in patients with AP when compared to the control group. During the following days, the concentration of pEla-1 rapidly decreased nearly to undetectable value on the third day. There was no significant difference between patients with mild and severe AP and according to aetiology. We suggest that pEla-1 has a little diagnostic value and does not provide additional information to that of cheaper and more widely available serum amylase and lipase.
Document Type
Publication order reference
U. Wereszczynska-Siemiatkowska, Department of Gastroenterology, Medical University, Bialystok, Poland
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.