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2009 | 59 | 1 | 57-66
Article title

Sjogren's syndrome: An old tale with a new twist

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Languages of publication
EN
Abstracts
EN
Sjogren's syndrome (SjS) is chronic autoimmune disease manifested by the loss of saliva and/or tear secretion by salivary and/or lacrimal glands, respectively. The pathogenesis of the disease remains elusive, perhaps due to the multiple triggers of the disease. However, substantial advances have been made in attempting to resolve the complexity of SjS using both animal models and human subjects. The primary objectives of this review are to provide a better understanding of the disease processes with major emphasis on the use of mouse models, how genetic predisposition plays a role in the natural history of the disease, as well as a presentation of new findings pertaining to the role of TH1, TH2, and TH17 cells in the pathogenesis of SjS.
Publisher

Year
Volume
59
Issue
1
Pages
57-66
Physical description
Contributors
author
author
author
References
Document Type
REVIEW
Publication order reference
Cuong Q. Nguyen, PhD, Department of Oral Biology, PO Box 100424, College of Dentistry, University of Florida, Gainesville, FL 32610, USA
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-4a50aa13-b2bb-33fa-ac38-8b766ff965ce
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