Micromanagement

• Authors: B. Szarzynska , Kulinska Z. Szweykowska- , A. Jarmolowski
• Languages of publication: EN

Abstracts

EN

MicroRNAs (miRNAs) are an abundant group of endogenous small (~22) noncoding RNAs, found both in plants and animals. The total number of sequences encoding miRNA in genomes of these organisms is estimated to be ~1% of all genes. miRNAs derive from longer precursor transcripts which adopt a fold- back structure. Mature miRNAs are incorporated into ribonucleoprotein complexes miRNPs and take part in negative control of genes' expression by cleavage of mRNAs or inhibition of the translation. miRNAs influence a great range of biological processes, such as cell proliferation, stem cell maitenance, timing of cell fate in developmental process, organ morphogenesis, programmed cell death and fat metabolism.

Keywords

EN

MIRNA; MIRNP; NCRNA; REGULATORY RNA; STRNA

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 2005
• Issue: 3
• Pages: 144-164

Contributors

author

B. Szarzynska

author

Kulinska Z. Szweykowska-

author

A. Jarmolowski

• Document Type: REVIEW
• Publication order reference: Bogna Szarzynska, Zaklad Ekspresji Genow, Instytut Biologii Molekularnej i Biotechnologii, Uniwersytet im. Adama Mickiewicza, ul. Miedzychodzka 5, 60-371 Poznan, Poland