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Journal
2005 | 3 | 144-164
Article title

Micromanagement

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Languages of publication
EN
Abstracts
EN
MicroRNAs (miRNAs) are an abundant group of endogenous small (~22) noncoding RNAs, found both in plants and animals. The total number of sequences encoding miRNA in genomes of these organisms is estimated to be ~1% of all genes. miRNAs derive from longer precursor transcripts which adopt a fold- back structure. Mature miRNAs are incorporated into ribonucleoprotein complexes miRNPs and take part in negative control of genes' expression by cleavage of mRNAs or inhibition of the translation. miRNAs influence a great range of biological processes, such as cell proliferation, stem cell maitenance, timing of cell fate in developmental process, organ morphogenesis, programmed cell death and fat metabolism.
Keywords
EN
Publisher

Journal
Year
Issue
3
Pages
144-164
Physical description
Contributors
References
Document Type
REVIEW
Publication order reference
Bogna Szarzynska, Zaklad Ekspresji Genow, Instytut Biologii Molekularnej i Biotechnologii, Uniwersytet im. Adama Mickiewicza, ul. Miedzychodzka 5, 60-371 Poznan, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-495dad1a-a4eb-36e4-954f-6172cb6aa832
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