PL EN


Preferences help
enabled [disable] Abstract
Number of results
2006 | 66 | 2 | 139-144
Article title

Effects of risperidone on auditory information processing in neuroleptic-naive patients with schizophrenia spectrum disorders

Content
Title variants
Languages of publication
EN
Abstracts
EN
Early effects of risperidone (2.5 ? 1 mg/day) on auditory information processing were investigated in 9 neuroleptic naive patients with schizophrenia spectrum disorders and 9 healthy controls by using event-related potentials (ERPs). ERPs were elicited during active auditory 'oddball' paradigm and were recorded before and after two weeks of treatment. Baseline P3 latencies were significantly delayed in patient group. Risperidone treatment did not change P3 amplitudes and latencies. However, P2 amplitudes were reduced in parallel with the clinical improvement measured by Positive and Negative Syndrome Scale (PANSS). Although risperidone did not change neural bases of active attention after two weeks of treatment, the reduction of P2 amplitude suggests that risperidone may affect auditory information processing in patients with schizophrenia spectrum disorders who never have been exposed to antipsychotic treatment.
Keywords
References
Document Type
ARTICLE
Publication order reference
Milena Korostenskaja, Department of Electrophysiology, Republican Vilnius Psychiatric Hospital, Parko-15, Vilnius, Lithuania, LT-11205
YADDA identifier
bwmeta1.element.element-from-psjc-45812e1a-beef-30ae-8623-876c9aae3eab
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.