EN
Luliberin ? luteinizing hormone-releasing hormone (LHRH) is the first link in hypothalamus-pituitary-gonads axis which participates in reproduction. This hormone and lutropin are released from immunological cells, however antagonists of LHRH inhibit this action. Some cytokines (IL-1?, GM-CSF) inhibit release of LHRH and other (IL-6, INF-?) stimulate this release.