PL EN


Preferences help
enabled [disable] Abstract
Number of results
1996 | 50 | 5 | 549-553
Article title

Lewis antigens in human colon carcinoma

Title variants
Languages of publication
PL
Abstracts
EN
Aberrant glycosylation is a common phenomenon accompanying colon carcinoma progression. The changes observed include increased expression of Lewis blood group family antigens, particularly Lex, sialyl Lex and sialyl Lea. Recently it was shown that these antigenic epitopes may play an important role in cell-cell homotypic as well as heterotypic adhesive interactions. This work presents a phenotypic characteristic of 11 human colon carcinoma cell lines of different degree of differentiation expression of potential ligands for endogenous cellular lectins: Lewis antigens, CEA and CD44v6 antigens was evaluated by cytofluorimetry. The aim of the work is to select adhesive and invasive colon carcinoma cells with specified cell surface antigen pattern, for studies on adhesive interactions with endothelial cells, occurring during early steps of metastasis.
Year
Volume
50
Issue
5
Pages
549-553
Physical description
Contributors
author
author
author
References
Document Type
article
Publication order reference
D.Dus, ul. R. Weigla 12, 53-114 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-3af2886a-c5e8-3366-8e18-0256faa04cc5
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.