As of 1 April 2026, the PSJD database will become an archive and will no longer accept new data. Current publications from Polish scientific journals are available through the Library of Science: https://bibliotekanauki.pl
Nicotine is a major constituent of tobacco and exerts a number of physiological effects. Metabolism of nicotine in animal and human tissues is reviewed. Clinical considerations regarding the problems of toxic effects of nicotine in human and molecular basis of carcinogen mechanism of nicotine derivatives are discussed.