The role of astrocytes in the physiology and pathology of the central nervous system

• Authors: I. Markiewicz , B. Lukomska
• Languages of publication: EN

Abstracts

EN

Astrocytes are the main class of neuroglia, serving a wide range of adaptive functions in the mammalian nervous system. They interact with neurons, providing structural, metabolic and trophic support for them. In pathological circumstances, astrocytes have the potential to induce neuronal dysfunction, but they can also play a neuroprotective role, releasing neuronal growth factors. Here we review recent findings regarding the role of astrocytes in the biology of the brain in physiological conditions, as well as their reaction following the onset of neurodegenerative disorders.

Keywords

EN

ASTROCYTE; MICROGLIA; NEURODEGENERATIVE DISEASE; NEURON

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Marceli Nencki Institute of Experimental Biology, Polish Academy of Sciences
• Journal: Acta Neurobiologiae Experimentalis
• Year: 2006
• Volume: 66
• Issue: 4
• Pages: 343-358

Contributors

author

I. Markiewicz

author

B. Lukomska

• Document Type: REVIEW
• Publication order reference: Barbara Lukomska, Department of Neuro-Repair, Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego St, 02-106 Warsaw, Poland