The effect of dorsal raphe nucleus (DRN) lesions on the locomotor activity rhythm in mice

• Authors: G. Barbacka-Surowiak , M. Gut
• Languages of publication: EN

Abstracts

EN

The study employed electrical lesions of dorsal raphe nucleus (DRN) to determine the functional significance of those nuclei in the regulation of wheel-running activity rhythm in mice in light/dark (LD 12:12), constant light (LL), and constant dark (DD) conditions. The wheel-running records showed that raphe nucleus lesions resulted in few days? decrease in common activity and amplitude in LD. The activity phase was not compact but in fragmentary form, especially in DD condition. In some animals an earlier onset of activity after DRN lesion in LD was observed. In LL extension of the rhythm period occurred. Destruction of DRN only slightly modulates the wheel-running circadian rhythm in mice.

Keywords

EN

CIRCADIAN RHYTHM; LOCOMOTOR ACTIVITY; RAPHE NUCLEI

Discipline

• ZOOLOGY: ZOOLOGY

• Publisher: Institute of Systematics and Evolution of Animals, Polish Academy of Sciences
• Journal: Folia Biologica
• Year: 2001
• Volume: 49
• Issue: 1-2
• Pages: 77-84

Contributors

author

G. Barbacka-Surowiak

author

M. Gut

• Document Type: ARTICLE
• Publication order reference: G. Barbacka-Surowiak, Department of Animal Physiology, Laboratory of Chronobiology, Institute of Zoology, Jagiellonian University, R. Ingardena 6, 30-060 Krakow, Poland