Transgenic mice as a tools for analysis of neoplastic transformation of T and B lymphocytes

• Authors: M. Kobzdej , L. Strzadala
• Languages of publication: PL

Abstracts

EN

This article describes the significance of the mouse transgenic model in elucidation of the role and the oncogenic potential of such genes as N-ras, pim-1, bcl-2, myc and p53. The role of gene targetting by homologous recombination in the study of preneoplastic state in the mice model was also discussed.

Keywords

EN

KNOCKOUT MICE; LEUKOMOGENESIS; ONCOGENE; TRANSGENIC MOUSE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1996
• Volume: 50
• Issue: 2
• Pages: 113-129

Contributors

author

M. Kobzdej

author

L. Strzadala

• Document Type: article
• Publication order reference: M.Kobzdej, Instytut Immunologii i Terapii Doswiadczalnej PAN, ul. Weigla 12, 53-114 Wroclaw, Poland