Transgenic mice as a tools for analysis of neoplastic transformation of T and B lymphocytes
Languages of publication
This article describes the significance of the mouse transgenic model in elucidation of the role and the oncogenic potential of such genes as N-ras, pim-1, bcl-2, myc and p53. The role of gene targetting by homologous recombination in the study of preneoplastic state in the mice model was also discussed.
Publication order reference
M.Kobzdej, Instytut Immunologii i Terapii Doswiadczalnej PAN, ul. Weigla 12, 53-114 Wroclaw, Poland