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Journal
1996 | 4 | 91-107
Article title

Perspectives for medical applications of synthetic oligonucleotides:antisense technology

Authors
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Languages of publication
EN
Abstracts
EN
Stability of stereoregular oligonucleotides towards selected nucleases, as well as the thermal stability of duplexes formed with DNA and RNa were investigated.Other strategies leading to antisense oligonucleotides try to avoid P-chirality by replacement of phosphates with achiral phosphorodithioates or moities like formacetal, sulphones, dietylsiloxanes etc.
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Journal
Year
Issue
4
Pages
91-107
Physical description
Contributors
author
author
References
Document Type
article
Publication order reference
W.J.Stec, Centre of Molecular and Macromolecular Studies, Dept. of Bioorganic Chemistry, Polish Academy of Sciences, Sienkiewicza St. 112, 90-363 Lodz, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-2c0561ca-813f-3a10-bef1-78a20f04233e
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