Staphylokinase - a new approach in the treatment of vascular disease

• Authors: T. Pietrucha , C, Watala
• Languages of publication: PL

Abstracts

EN

Staphylokinase is a new promising therapeutic agent with an expanding clinical application in the treatment of vascular disease.In the present paper the autors discuss the biochemical and physiological properties of the recombinant protein.The methods and techniques of protein synthesis, isolation and purification, including the genetic engineering approaches are critically summarized.The emphasis is put onto the critical review of the experiments concerning the use of ataphylokinase in thrombotic models in experimental animals.Moreover, we discuss the potential role and advantages of staphylokinase over the other thrombolytic agents in the treatment of cardiovascular disease in humans.

Keywords

EN

FIBRYNOLYSIS; MYOCARDIAL INFARCTION; PLASMINOGEN ACTIVATOR; STAPHYLOKINASE; THROMBOLYTIC AGENT; THROMBOLYTIC THERAPY; VASCULAR DISEASE

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1996
• Issue: 3
• Pages: 43-51

Contributors

author

T. Pietrucha

author

C, Watala

• Document Type: article
• Publication order reference: T.Pietrucha