Plasmids R577 and R785 decrease the resistance of Escherichia coli K12 strain W1485 to bactericidal action of normal serum
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The role of plasmids of drug resistance R577 and R785 in the development of susceptibility of Escherichia coli K12 strain W1485 to the bactericidal action of serum was studied. Plasmids R577 and R785 were transfered to cells of strain W1485 by means of conjugation. The susceptibility of cells containing the plasmid to serum was compared to that of cells lacking the plasmid. It was found that plasmids R577 and R758 sensitize bacteria to the action of serum.
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S. Jankowski, Department of Biology, Medical University, ul. Mikulicza-Radeckiego 9, 50-367 Wroclaw, Poland