Macrophages and HIV-1-associated dementia
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One of the strongest predictors for HIV-1-associated dementia is the presence of monocytic infiltration in perivascular areas of the brain. Therefore, macrophages have been suggested to play a major role in the development of this disease. This review focuses on possible mechanisms through which the macrophage may enhance disease progression by mediating neuronal damage.
Publication order reference
L. A. Bovem, Department of Clinical Neurosciences, University of Calgary, Canada