PL EN


Preferences help
enabled [disable] Abstract
Number of results
1996 | 56 | 2 | 555-559
Article title

Differential expression of NMDA-evoked 45Ca release in rat hippocampal regions in vivo

Selected contents from this journal
Title variants
Languages of publication
EN
Abstracts
EN
Recently we detected NMDA-induced 45Ca release in the rat dentate gyrus in vivo, attributable to the Ca2+ release (CICR) from the endoplasmic reticulum via ryanodine channels.In these experiments we compare expression of NMDA-evoked 45Ca release in the rat dentate gyrus (DG), CA1 and subiculum (SUB).The release of 45Ca was studied using in vivo prelabelled hippocampal regions.It was shown thet NMDA-induced 45Ca release, highly pronounced in the rat DG/CA4, is significantly less expressed in the CA1, whereas in the SUB and NMDA-evoked decrease in 45Ca efflux was noted.This corresponds to distribution of ryanodine receptors in the rat hippocampus, known from the literature.Expression of NMDA-evoked 45Ca release in these rat hippocampal regions which are enriched in ryanodine receptors supports our working hypothesis that CICR via ryanodine channels may be mainly responsible for 45Ca release.
Keywords
Publisher

Year
Volume
56
Issue
2
Pages
555-559
Physical description
Contributors
author
author
References
Document Type
article
Publication order reference
J.Lazarewicz
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-1b5dded3-f293-3f9f-bbb0-d1588e8caf48
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.