Both vaccines ware safe and immunogenic when administered in foxes and minks.Among the inactivated vaccines, the MEV-143 virus inactivated with betha-priopiolactone demonstrated best antigenic properties.The level of antibodies in the sera of immunized animals was equal to antibody titre induced by attenuated virus of polish vaccine Faxvac Parwo or reference vaccines Biovac D and Nordent vet.