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Journal
2002 | 1 | 136-141
Article title

BSE- identification and prophylactics

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Languages of publication
PL
Abstracts
EN
Prion diseases (for example: scrape of sheep, BSE, CJD of humans) are among the most notable central nervous system degenerative disorders caused by the accumulation of modified cellular protein. The conversion of PrP(C) (the normal cellular protein) into PrP(Sc) (the abnormal disease-causing isoform) involves a conformation change whereby the ?-helical content diminishes and the amount of ? sheet increases. PrP (Sc) is partially resistant to proteases, temperature, high and low pH. Because the incidence of prion diseases is due to several factors, various efforts need to be taken to reduce the scale and consequences of the disease. They include post-mortem and in vivo diagnosis and prophylactics, i.e. monitoring of animals and feed control.
Keywords
Journal
Year
Issue
1
Pages
136-141
Physical description
References
Document Type
REVIEW
Publication order reference
E. Slota, Zaklad Immuno i Cytogenetyki, Instytut Zootechniki, 32-083 Balice k. Krakowa, Poland
YADDA identifier
bwmeta1.element.element-from-psjc-184f01aa-ff6c-3c4a-9ec4-f313759a5e69
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