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2002 | 43 | 1 | 85-91
Article title

Analysis of associations of PIT1 genotypes with growth, meat quality and carcass composition traits in pigs

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Abstracts
EN
PIT1 was chosen as a candidate gene to investigate its associations with growth, meat quality and carcass composition traits in the pig. PIT1 is known as the pituitary-specific activator of the growth hormone in several mammals. Furthermore, PIT1 is a positive regulatory factor of prolactin and thyroid-stimulating hormone b. PIT1 is a member of the POU-domain family of genes and is located on porcine chromosome 13. Two informative three-generation families of the University of Hohenheim were used for the presented investigations. The families were based on crosses of the European Wild boar (W) ? Pietrain (P) and Meishan (M) ? Pietrain (P). Each family included 310 F2 animals. A RsaI (PCR) RFLP described by YU et al. (1994) was used for genotyping the animals. Altogether over 50 parameters of growth, meat quality, carcass composition and stress susceptibility were evaluated concerning their associations with RsaI PCR-RFLP. The statistical model of association analyses was used including fixed effects of sex, family, PIT1 genotypes and covariate age at slaughter. Taking the significance level of p < 0.05 as the basis, fourteen traits of growth and carcass composition were associated with PIT1 genotypes in family W ? P. Results from this study suggest that there are contributions of PIT1 gene to variations in the analysed performance traits in pigs. The influence of PIT1 genotypes could not be confirmed under the supposition of a genome-wide test limit.
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43
Issue
1
Pages
85-91
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ARTICLE
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J. Bieniek, Department of Genetics and Animal Breeding, Agricultural University of Cracow, Al. Mickiewicza 24/28, 30-059 Krakow, Poland
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bwmeta1.element.element-from-psjc-159fbe84-ecf7-3be5-a4f2-0f2d4910d219
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