Gene expression in learning processes

• Authors: L. Kaczmarek
• Languages of publication: EN

Abstracts

EN

It has repeatedly been shown that long-term memory formation involves neuronal gene expression. In this article several different roles for neuronal gene function in a context of learning are considered: maintenance of neural functioning, replenishment of cellular elements that are exhausted in response to massive neuronal stimulation accompanying behavioral training, maintenance of the plastically reorganized neuronal connections, and finally integration of information at the level of transcription factor-promoter interaction. It is strongly advocated that only careful scrutiny of learning-related gene expression phenomena may aid in understanding of the complex learning process.

Keywords

EN

BEHAVIOUR; C-FOS; INFORMATION PROCESSING; LONG-TERM MEMORY; TRANSCRIPTION FACTOR

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Marceli Nencki Institute of Experimental Biology, Polish Academy of Sciences
• Journal: Acta Neurobiologiae Experimentalis
• Year: 2000
• Volume: 60
• Issue: 3
• Pages: 419-424

Contributors

author

L. Kaczmarek

• Document Type: review
• Publication order reference: L. Kaczmarek, Department for Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland, Email: [e-mail]