Preferential segregation of marker chromosomes 14 and 18 in mouse recombinant inbred strains derived from the KE and CBA/Kw inbred strains
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The segregation pattern of chromosomes 14 and 18 were analysed in recombinant inbred strains of mice developed from KE and CBA/Kw strains. The analysis was possible owing to the fact that the C-band on chromosomes 14 of the CBA/Kw strain and that of chromosome 18 of the KE strain show size polymorphism: while the CBA/Kw mice have a small sized C-band on chromosome 14, the KE mice show small C-bands on chromosome 18. Chromosomes were identified by G-banding and FISH. The results show that the chromosomes with small centromeric chromatin segregate preferentially.
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M. Lenartowicz, Department of Genetics and Evolution, Institute of Zoology, Jagiellonian University, R. Ingardena 6, 30-060 Krakow, Poland, E-mail: Lena@zuk.iz.uj.edu.pl