Isulfhydryl reagents with K+ transport in adrenal chromaffin granules
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In the present study the functional role of SH groups in the Ca2+ -independent K+ selective channel activity in the membrane of bovine adrenal gland chromaffin granules has been studied. Ionic channel activity has been estimated using 86Rb+, a K+ analogue, flux measurements. The inhibition of chromaffin granules K+ channel by SH modifying agents, such as N ethylmaleimide, mersalyl and phenylarsenoxide, is described.
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A.Szewczyk, Department of Molecular and Cell Neurobiology, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093, Warsaw, Poland, Email:email@example.com