MspI polymorphisms in the 3rd intron of the swine POU1F1 gene and their associations with growth performance

• Authors: C. Song , B. Gao , Y. Teng , X. Wang , Z. Wang , Q. Li , H.F. Mi , R. Jing , J. Mao
• Languages of publication: EN

Abstracts

EN

The study aimed to compare MspI polymorphisms in the 3rd intron of the porcine gene encoding the pituitary-1 transcription factor (Pit-1, renamed as POU1F1) among 5 breeds and to determine the associations between its genotypes and growth performance in a commercial pig population by using the PCR-RFLP technique. Significant differences in genotypic and allelic frequencies were found between the meat-type and fat-type breeds (P < 0.05), and between miniature pigs and others (P < 0.05). No breed deviated from the Hardy-Weinberg equilibrium (verified by chi-square test). The general linear model analysis revealed that higher body weight on day 180 (BW180) and average daily gain (ADG) were significantly associated with POU1F1 DD genotype (P < 0.05). The differences in BW180 and ADG between DD pigs and both CD and CC pigs were significant (P < 0.05), and the DD pigs had a significantly higher body weight on day 45 (BW45) and on day 70 (BW70) than CC pigs (P < 0.05). All measured growth traits, except for body weight at birth (BWB), showed higher values in DD pigs. The D allele had a favorable positive effect on growth traits. Thus POU1F1 is a potential major gene or marker for growth traits.

Keywords

EN

GROWTH; PIG; POLYMORPHISM

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2005
• Volume: 46
• Issue: 3
• Pages: 285-289

Contributors

author

C. Song

author

B. Gao

author

Y. Teng

author

X. Wang

author

Z. Wang

author

Q. Li

author

H.F. Mi

author

R. Jing

author

J. Mao

• Document Type: ARTICLE
• Publication order reference: Chengyi Song, College of Animal Science and Technology, Yangzhou University, Yangzhou city, 12 Wenhui East Road, Jiangsu Province 225009, P.R. China