Biological activity of the isothiazole derivatives
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The isothiazole ring was first synthesized in 1956 by Adams and Slack. It was known earlier in condensed structures such as benzisothiazole (saccharin for example). The first found natural origin isothiazole derivative was brassilexin ? a phytoalexin from Brassica juncea. In this review diverse biological activity of isothiazole derivatives and their application has been presented.
Publication order reference
R. Miedzybrodzki, Instytut Immunologii i Terapii Doswiadczalnej, Polish Academy of Sciences, ul. R.Weigla 12, 53-114 Wroclaw, Poland