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Number of results
1997 | 51 | 4 | 457-471

Article title

The effect of methylglyoxal in diabetic complications development

Title variants

Languages of publication

PL

Abstracts

EN
The formation of methylglyoxal is increased during hyperglycemia associated with diabetes mellitus. Enhanced methylglyoxal concentration in biological systems is associated with increased reversible and inreversible modification of protein. The chronic exposure to high methylglyoxal concentrations appears to be linked to the development of diabetic complications. Intervention with aldose reductase inhibitors or aminoguanidine, which is an efficient scavenger of methylglyoxal, in diabetes mellitus may prevent increased methylglyoxal concentrations.

Year

Volume

51

Issue

4

Pages

457-471

Physical description

Contributors

References

Document Type

article

Publication order reference

D.Piskorska, ul. Armii Krajowej 48, 40-698 Katowice, Poland

Identifiers

YADDA identifier

bwmeta1.element.element-from-psjc-096d7956-2257-37ae-bb69-b4f1991acc01
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