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1997 | 51 | 4 | 457-471
Article title

The effect of methylglyoxal in diabetic complications development

Title variants
Languages of publication
PL
Abstracts
EN
The formation of methylglyoxal is increased during hyperglycemia associated with diabetes mellitus. Enhanced methylglyoxal concentration in biological systems is associated with increased reversible and inreversible modification of protein. The chronic exposure to high methylglyoxal concentrations appears to be linked to the development of diabetic complications. Intervention with aldose reductase inhibitors or aminoguanidine, which is an efficient scavenger of methylglyoxal, in diabetes mellitus may prevent increased methylglyoxal concentrations.
Year
Volume
51
Issue
4
Pages
457-471
Physical description
Contributors
References
Document Type
article
Publication order reference
D.Piskorska, ul. Armii Krajowej 48, 40-698 Katowice, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-096d7956-2257-37ae-bb69-b4f1991acc01
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