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Journal
2002 | 1 | 87-104
Article title

Neoplastic cell transformation by viruses

Content
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Languages of publication
PL
Abstracts
EN
Tumor-inducing viruses occur in several taxonomic groups. All RNA tumor viruses belong to retrovirus family, but the DNA tumor viruses come from several different groups. Their oncogenic potential is associated with their replication strategy, and in a vast majority of cases oncogenic transformation occurs only if the viral life cycle is aborted. The oncogenic phenotype results from discrete changes in the expression of key cellular control genes: oncogenes and tumor suppressor genes. Most often, the retroviruses cause the activation of oncogenes, and DNA tumor viruses usually target tumor suppressor genes.
Journal
Year
Issue
1
Pages
87-104
Physical description
References
Document Type
REVIEW
Publication order reference
M. Schmidt, Zaklad Wirusologii Molekularnej, Instytut Biologii Molekularnej i Biotechnologii, Uniwersytet im. Adama Mickiewicza, ul. Miedzychodzka 5, 60-371 Poznan, Poland
YADDA identifier
bwmeta1.element.element-from-psjc-07f966f3-045e-394c-92c3-7a4c244ac261
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