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2000 | 48 | 3 | 143-150
Article title

A burgeoning family of biological mediators: chemokines and chemokine receptors

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Languages of publication
EN
Abstracts
EN
Chemokines are a superfamily of pro-inflammatory polypeptide cytokines that selectively attract and activate different cell types. Most of its members are small proteins that exhibit conserved cysteines in specific positions. Chemokines activate cells through their binding to shared or unique cell surface receptors which belong to the seven-transmembrane (STM), G-protein-coupled receptors (GPCRs). The large number of chemokines and chemokine receptors are indicative of the importance of these molecules in a variety of pathophysiological conditions.
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Year
Volume
48
Issue
3
Pages
143-150
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Contributors
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author
author
author
author
author
References
Document Type
REVIEW
Publication order reference
Y. Le, Laboratory of Molecular Immunoregulation, Division of Basic Sciences, National Cancer Institute-Frederick Cancer Research and Development Center, Frederick, MD 21702, USA,
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-06d06577-d17b-346c-8056-71d488c6e2b9
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