Distribution of HLA-C alleles determined by PCR-SSP in population of Low Silesia
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We typed 100 unrelated healthy Poles from Low Silesia region for HLA-C using low resolution PCR-SSP and compared observed allele frequencies with data published for other human populations. Poles appeared to be most similar to Germans and Englishmen, and were more distant from French, Catalans and Basques and dissimilar to non-Caucasoids from Equatorial Guinea and Japan. It would be interesting to HLA-C-type other Slavian and non-Slavian people from Middle and Eastern Europe for comparison.
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M. Prussak, Laboratory of Immunogenetics, Department of Clinical Immunology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland