Nitryle hydrytase ? Ligot activated industrial enzyme

• Authors: L. Peplowski , K. Kubiak , W. Nowak
• Languages of publication: PL

Abstracts

EN

Since 1985, nitrile hydratases, metallo-enzymes present in bacteria from genus Rhodococcous, have been used for industrial production of acrylamide and related chemicals. The unique active site of both Fe- and Co-nitrile hydratases contains oxidized cysteines. Despite many efforts, details of the catalytic mechanism of activity and high selectivity remain unknown. Molecular structures, possible routes of hydration and prospects for applications of these photoactive enzymes in nanotechnology are discussed in this review.

Keywords

EN

BIOCATALYSIS; NITRILE HYDRATASE; PHOTOACTIVE ENZYME

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 2007
• Issue: 1
• Pages: 63-76

Contributors

author

L. Peplowski

author

K. Kubiak

author

W. Nowak

• Document Type: REVIEW
• Publication order reference: Lukasz Peplowski, Zespol Teoretycznej Biofizyki Molekularnej, Instytut Fizyki, Uniwersytet Mikolaja Kopernika, ul. Grudziadzka 5, 87-100 Torun, Poland