1,3-OXAZOLIDIN-5-ONES DERIVED FROM PROLINE AS CHIRAL COMPONENTS IN THE SYNTHESIS OF PREDICTIVE ENANTIOSELECTIVE COUPLING REAGENTS

Kasperowicz-Frankowska, Katarzyna; Kolesińska, Beata; Gzik, Anna; Jastrząbek, Konrad; Kaminski, Zbigniew J.

doi:10.32383/appdr/78726

Journal

Acta Poloniae Pharmaceutica - Drug Research

2018 | 75 | 4 | 921-927

Article title

1,3-OXAZOLIDIN-5-ONES DERIVED FROM PROLINE AS CHIRAL COMPONENTS IN THE SYNTHESIS OF PREDICTIVE ENANTIOSELECTIVE COUPLING REAGENTS

Authors

Katarzyna Kasperowicz-Frankowska , Beata Kolesińska , Anna Gzik , Konrad Jastrząbek , Zbigniew J. Kaminski

Content

Full texts:

download-?file=File%2FActa_Poloniae%2F2018%2F4%2F921.pdf.pdf

Download

Title variants

Languages of publication

Abstracts

1,3-Oxazolidin-5-ones derived from both enantiomers of proline and trichloroacetaldehyde were prepared and applied as amine component in the synthesis of chiral predictive triazine based coupling reagents. The usefulness of these reagents in the condensations yielding enantiomerically enriched products from racemic substrates was presented.

Keywords

enantioselective condensation peptide synthesis chirality transfer on nitrogen chiral nitrogen atom triazine coupling reagent

Journal

Acta Poloniae Pharmaceutica - Drug Research

Year

2018

Volume

Issue

Pages

921-927

Physical description

Dates

published

2018-08-31

Contributors

author

Katarzyna Kasperowicz-Frankowska

author

Beata Kolesińska

author

Anna Gzik

author

Konrad Jastrząbek

author

Zbigniew J. Kaminski

References

Document Type

Publication order reference

Identifiers

DOI

10.32383/appdr/78726

YADDA identifier

bwmeta1.element.doi-10_32383_appdr_78726