IMPACT OF EXCIPIENTS ON PHARMACEUTICAL AVAILABILITY OF FOLIC ACID FROM TABLETS

Ostróżka-Cieślik, Aneta; Dolińska, Barbara; Ryszka, Florian

doi:10.32383/appdr/78082

Journal

Acta Poloniae Pharmaceutica - Drug Research

2018 | 75 | 4 | 959-963

Article title

IMPACT OF EXCIPIENTS ON PHARMACEUTICAL AVAILABILITY OF FOLIC ACID FROM TABLETS

Authors

Aneta Ostróżka-Cieślik , Barbara Dolińska , Florian Ryszka

Content

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Abstracts

The impact of excipients contained in individual formulations on the pharmaceutical availability of folic acid was investigated. The release rate of the active substance and the disintegration time of the tablets were analysed. It has been found that in the presence of sorbitol, glucose and starch, 100% of folic acid is released within 60 minutes, and in the presence of lactose and starch - 95%, and the release rates for them are 0.0717 min-1 and 0.0555 min-1 respectively.

Keywords

folic acid dietary supplements dissolution testing

Journal

Acta Poloniae Pharmaceutica - Drug Research

Year

2018

Volume

Issue

Pages

959-963

Physical description

Dates

published

2018-08-31

Contributors

author

Aneta Ostróżka-Cieślik

author

Barbara Dolińska

author

Florian Ryszka

References

Document Type

Publication order reference

Identifiers

DOI

10.32383/appdr/78082

YADDA identifier

bwmeta1.element.doi-10_32383_appdr_78082