Contrast-enhanced Magnetic Resonance Imaging of lung cell cultures

• Authors: Zuzanna Bober , Katarzyna Pogoda , David Aebisher , Jacek Tabarkiewcz , Dorota Bartusik-Aebisher
• Languages of publication: EN

Abstracts

EN

Lung cancer is one of the most common types of cancer diagnosed, and the development of methods to image diseased lung tissue by MRI is of utmost importance. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) was used to noninvasively evaluate spin-spin relaxation time, T1, of lung cell cultures infused with various clinical gadolinium-based contrast media for imaging. In this study we used a clinical 1.5 Tesla scanner and the contrast agents: Omniscan, MultiHance, Gadovist and ProHance. A significant five-fold reduction of T1 relaxation time was obtained.

Keywords

EN

Lung cancer; cell cultures; magnetic resonance imaging; contrast media; Gadolinium

• Journal: Acta Poloniae Pharmaceutica - Drug Research
• Year: 2020
• Volume: 77
• Issue: 2
• Pages: 251-258

Dates

published

2020-04-29

Contributors

author

Zuzanna Bober

author

Katarzyna Pogoda

author

David Aebisher

author

Jacek Tabarkiewcz

author

Dorota Bartusik-Aebisher

Identifiers

DOI

10.32383/appdr/118741