HPLC-DAD-ESI/MS Analysis of Arnica TM Constituents
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The herbal drugs obtained from Arnica montana flowers are known for their anti-inflammatory activity. However, there is no detailed data on chemical constituents of the whole Arnica plant. HPLC-DAD-ESI/MS analysis of the whole Arnica montana plant (Arnica TM), used in the preparation of allopathic and homeopathic medicinal products, has been conducted. The qualitative and quantitative analysis comprised phenolic acids, flavonoids and sesquiterpene lactones – helenalin and dihydrohelenaline esters identified earlier in Arnica flowers. The analyzed material showed to be a rich source of caffeoylquinic acid (CQA) derivatives, especially 3,5-di-O-caffeoylquinic acid. According to the literature data, anti-inflammatory activity of extracts from the whole Arnica montana plant can be due to CQA presence as dominating compounds.
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