PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL EVALUATION OF FORSSKAOLEA VIRIDIS AERIAL PARTS

• Authors: Taha A. El-Bassossy , Fatma A. Ahmed , Amani M. El-Mesallamy
• Languages of publication: EN

Abstracts

EN

The chemical investigation of the chloroform and ethyl acetate extracts of the aerial parts of Forsskaolea viridis Ehrenb. ex Webb (Family: Urticaceae) led to isolation eight compounds for the first time from this plant, while two phenolic compounds, identified as p-coumaric and caffeic acids as well as six flavonoid compounds identified as 5-hydroxy-6,7,3',4'-tetramethoxy flavone, chrysoeriol, acacetin, chrysoeriol-7-O-β-D-glucoside, kaempferol-3-O-(2"-O-E--p-coumaroyl)-β-D-glucoside and isovetixin. The chemical structure of the isolated compounds was established by spectroscopic methods including UV, MS, 1H-NMR, and 13C-NMR. Antimicrobial, antioxidant and cytotoxic activities of the ethyl acetate and chloroform extracts were evaluated. The ethyl acetate extract exhibited strong antimicrobial activity (12-30 mm) against the tested strains. The ethyl acetate and chloroform extracts showed fair antioxidant and cytotoxicity.

Keywords

EN

antimicrobial; flavonoids; phenolics; antitumor; Forsskaolea viridis

• Journal: Acta Poloniae Pharmaceutica - Drug Research
• Year: 2019
• Volume: 76
• Issue: 5
• Pages: 815-823

Dates

published

2019-10-30

Contributors

author

Taha A. El-Bassossy

author

Fatma A. Ahmed

author

Amani M. El-Mesallamy

Identifiers

DOI

10.32383/appdr/108519