THE RADIOSTABILITY OF BETAMIPRON IN THE SOLID STATE

• Authors: Przemysław Zalewski , Karolina Kilińska , Judyta Cielecka-Piontek , Robert Skibiński , Andrzej Miklaszewski , Waldemar Bednarski
• Languages of publication: EN

Abstracts

EN

The influence of ionising radiation on physicochemical properties of betamipron in solid state was studied. No changes for betamipron irradiated with a dose of 25 kGy, required to attain sterility, was observed by spectroscopic and chromatographic methods. Solid betamipron has proven to be very stable on irradiation, and irradiation has been found to be a suitable method for its sterilization.

Keywords

EN

EPR; radiation sterilization; radiostability; Q-TOF; betamipron

• Journal: Acta Poloniae Pharmaceutica - Drug Research
• Year: 2019
• Volume: 76
• Issue: 4
• Pages: 629-634

Dates

published

2019-08-30

Contributors

author

Przemysław Zalewski

author

Karolina Kilińska

author

Judyta Cielecka-Piontek

author

Robert Skibiński

author

Andrzej Miklaszewski

author

Waldemar Bednarski

Identifiers

DOI

10.32383/appdr/103882