PL EN


Preferences help
enabled [disable] Abstract
Number of results
2019 | 2 | 1 | 28-35
Article title

Comparison of clinical and echocardiographic parameters in patients with hypertrophic cardiomyopathy under and over 60 years of age

Content
Title variants
Languages of publication
EN
Abstracts
EN
Background Hypertrophic Cardiomyopathy (HCM) is one of the most common genetic myocardial diseases. Transthoracic echocardiography which includes speckle tracking technique is tool for HCM diagnosis and monitoring the course of the disease. The aim of this study was to compare clinical and echocardiographic parameters in HCM patients older and younger than 60 years old (yo). Material and methods We prospectively enrolled 53 HCM patients, who were divided into two groups: younger and older than 60 yo. Clinical parameters, standard echocardiographic indices, as well as strain parameters were assessed and compared between the groups. Results The older subgroup was characterized by a higher prevalence of coronary artery disease. In the younger subgroup the incidence of atrial fibrillation was quite high, which occurs far more often than in the general population. Echocardiographic analysis showed worse diastolic function in older, as well as lower volume of the LV. The global longitudinal strain was worse in <60 patients. The 3D strain parameters differed significantly between the groups: the area and radial strains were worse in younger patients. Conclusions HCM patients older and younger than 60 yo differ significantly in terms of clinical and echocardiographic parameters.
Year
Volume
2
Issue
1
Pages
28-35
Physical description
Dates
published
2019-06-04
received
2018-07-16
accepted
2018-11-08
References
  • Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, et al. 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy. J Am Coll Cardiol. 2011;58(25):e212-e260.
  • Elliott PM, Anastasakis A, Borger MA, Borggrefe M, Cecchi F, Charron P, et al. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy. Eur Heart J. 2014;35(39):2733–79.3.
  • Debonnaire P, Thijssen J, Leong DP, Joyce E, Katsanos S, Hoogslag GE, et al. Global longitudinal strain and left atrial volume index improve prediction of appropriate implantable cardioverter defibrillator therapy in hypertrophic cardiomyopathy patients. Int J Cardiovasc Imaging. 2014;30(3):549–58.
  • Iio C, Inoue K, Nishimura K, Fujii A, Nagai T, Suzuki J, et al. Characteristics of Left Atrial Deformation Parameters and Their Prognostic Impact in Pa- tients with Pathological Left Ventricular Hypertrophy: Analysis by Speckle Tracking Echocardiography. Echocardiography. 2015; 8;32(12):1821–30.
  • Popović ZB, Kwon DH, Mishra M, Buakhamsri A, Greenberg NL, Thamilarasan M, et al. Association Between Regional Ventricular Function and Myocardial Fibrosis in Hypertrophic Cardiomyopathy Assessed by Speckle Tracking Echocardiography and Delayed Hyperenhancement Magnet- ic Resonance Imaging. J Am Soc Echocardiogr. 2008;21(12):1299–305.
  • Vergé M-P, Cochet H, Reynaud A, Morlon L, Peyrou J, Vincent C, et al. Characterization of hypertrophic cardiomyopathy according to global, regional, and multi-layer longitudinal strain analysis, and prediction of sudden cardiac death. Int J Cardiovasc Imaging. 2018;34(7):1091–8.
  • Zhang H-J, Wang H, Sun T, Lu M-J, Xu N, Wu W-C, et al. Assessment of left ventricular twist mechanics by speckle tracking echocardiogra- phy reveals association between LV twist and myocardial fibrosis in patients with hypertrophic cardiomyopathy. Int J Cardiovasc Imaging. 2014;30(8):1539–48.
  • Fijałkowski M, Nowak R. Speckle tracking technique; Clinical Echocardiography; Lipiec P, Hoffman P et al; 1 ed., Warsaw, Total Project, 2017:50-57.
  • Maron BJ, Casey SA, Haas TS, Kitner CL, Garberich RF, Lesser JR. Hypertrophic Cardiomyopathy With Longevity to 90 Years or Older. Am J Cardiol. 2012;109(9):1341–7.
  • Maron BJ, Casey SA, Hauser RG, Aeppli DM. Clinical course of hypertrophic cardiomyopathy with survival to advanced age. J Am Coll Cardiol. 2011; 58:2313-2321.
  • Maron BJ, Rowin EJ, Casey SA, Haas TS, Chan RHM, Udelson JE, et al. Risk Stratification and Outcome of Patients With Hypertrophic Cardiomyo- pathy >=60 Years of Age. Circulation. 2012;127(5):585–93.
  • Belghiti H, et al. Automated function imaging: a new operator-independent strain method for assessing left ventricular function. Arch Cardio- vasc Des. 2008; 101(3): 163-169.
  • Leitman M, Lysiansky M, Lysyansky P, Friedman Z, Tyomkin V, Fuchs T, et al. Circumferential and Longitudinal Strain in 3 Myocardial Layers in Normal Subjects and in Patients with Regional Left Ventricular Dysfunction. J Am Soc Echocardiogr. 2010;23(1):64–70.
  • Lipiec P, et al. Transthoracic echocardiography in adults – guidelines of the Working Group on Echocardiography of Polish Cardiac Society. Kardiol Pol. 2018; 76(2):488-493.
  • Iio C, Inoue K, Nishimura K, Fujii A, Nagai T, Suzuki J, et al. Characteristics of Left Atrial Deformation Parameters and Their Prognostic Impact in Pa- tients with Pathological Left Ventricular Hypertrophy: Analysis by Speckle Tracking Echocardiography. Echocardiography. 2015;32(12):1821–30.
  • Thorstensen A, Dalen H, Hala P, Kiss G, D’hooge J, Torp H, et al. Three-Dimensional Echocardiography in the Evaluation of Global and Regional Function in Patients with Recent Myocardial Infarction: A Comparison with Magnetic Resonance Imaging. Echocardiography. 2013;30(6):682–92.
  • Fujimoto K, Inoue K, Saito M, Higashi H, Kono T, Uetani T, et al. Incremental value of left atrial active function measured by speckle tracking echocardiography in patients with hypertrophic cardiomyopathy. Echocardiography. 2018;35(8):1138–48.
  • Aly MFA, Brouwer WP, Kleijn SA, van Rossum AC, Kamp O. Three-dimensional speckle tracking echocardiography for the preclinical diagnosis of hypertrophic cardiomyopathy. Int J Cardiovasc Imaging. 2014;30(3):523–33.
  • Hees PS, Fleg JL, Dong S-J, Shapiro EP. MRI and echocardiographic assessment of the diastolic dysfunction of normal aging: altered LV pressure decline or load? Am J Physiol -Heart Circ Physiol. 2004;286(2):H782–8.
  • PiepoliMF,HoesAW,AgewallS,AlbusC,BrotonsC,CatapanoAL,etal.2016EuropeanGuidelinesoncardiovasculardiseasepreventioninclinical practice. Eur Heart J. 2016;37(29):2315–81.
  • KirchhofP,BenussiS,KotechaD,AhlssonA,AtarD,CasadeiB,etal.2016ESCGuidelinesforthemanagementofatrialfibrillationdevelopedin collaboration with EACTS. Eur Heart J. 2016;37(38):2893–962.
  • NaguehSF,SmisethOA,AppletonCP,ByrdBFIII,DokainishH,EdvardsenT,etal.RecommendationsfortheEvaluationofLeftVentricularDias- tolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J – Cardiovasc Imaging . 2016;17(12):1321–60.
  • LangRM,BadanoLP,Mor-AviV,AfilaloJ,ArmstrongA,ErnandeL,etal.RecommendationsforCardiacChamberQuantificationbyEchocardiog- raphy in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J – Cardiovasc Imaging. 2015;16(3):233–71.
  • VieiraMJ,TeixeiraR,GonçalvesL,GershBJ.LeftAtrialMechanics:EchocardiographicAssessmentandClinicalImplications.JAmSocEchocardi- ogr. 2014;27(5):463–78.
  • SarvariSI,HaugaaKH,StokkeTM,AnsariHZ,LerenIS,HegbomF,etal.Strainechocardiographicassessmentofleftatrialfunctionpredictsrecur- rence of atrial fibrillation. Eur Heart J – Cardiovasc Imaging. 2015;17(6):660–7.
  • ZhangL.Hypertrophiccardiomyopathy:Canthenoninvasivediagnostictestingidentifyhighriskpatients?WorldJCardiol.2014;6(8):764-770.
  • Voigt J-U, Pedrizzetti G, Lysyansky P, Marwick TH, Houle H, Baumann R, et al. Definitions for a Common Standard for 2D Speckle Tracking Echocardiography: Consensus Document of the EACVI/ASE/Industry Task Force to Standardize Deformation Imaging. J Am Soc Echocardiogr. 2015;28(2):183–93.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.doi-10_31373_ejtcm_99667
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.