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2019 | 1 | 2 | 41-52
Article title

Clinical and epidemiological aspects of acute pancreatitis – 10 years of single-center experience

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Abstracts
EN
Background We can observe an increase in acute pancreatitis (AP) incidence in the recent years. Material and methods Retrospective clinical data analysis of 370 patients with AP, hospitalized between 2007 and 2016 at our Department. Results AP was diagnosed during 406 hospitalisation in 370 patients [average age 52.15 (21-93), 237(64.05%) male]. AP of high clinical severity was diagnosed in 60/370 (16.22%) patients. Average time of hospitalisation was 16.13 (1-121) days. Mortality was 12/406 (2.96%). The after effect of AP in form of parapancreatic fluid reservoirs was diagnosed in 202/406 (54.59%) cases. Comparing the early phase of the study (2007-2011) and the later one (2012-2016) a shorter time of hospitalisation was proven and a lower mortality of the patients in the later phase of the study. Analysis of patients' blood tests revealed that patients with severe AP have significantly elevated levels of inflammatory parameters and amylase comparing to group with mild and moderate AP, during the first days of hospitalisation. Conclusions The development of conservative treatment options for AP, especially in early stages of the illness, has significantly shortened the duration of hospitalisation of patients with AP at our Department.
Year
Volume
1
Issue
2
Pages
41-52
Physical description
Dates
published
2019-02-05
received
2018-05-23
accepted
2018-11-04
References
  • Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis − 2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102-11.
  • Thoeni RF. The revised Atlanta classification of acute pancreatitis: its importance for the radiologist and its effect on treatment. Radiology. 2012;262(3): 751-64.
  • Makhija R, Kingsnorth AN. Cytokine storm in acute pancreatitis. J Hepatobiliary Pancreat Surg. 2002;9(4):401-10.
  • Bhatia M, Brady M, Shokuhi S, Christmas S, Neoptolemos JP, Slavin J. Inflammatory mediators in acute pancreatitis. J Pathol. 2000;190(2):117-25.
  • Kozieł D, Głuszek S. Epidemiology of acute pancreatitis in Poland – selected problems. Med Stud. 2016;32(1):1-3.
  • Głuszek S, Kozieł D. Prevalence and progression of acute pancreatitis in the świętokrzyskie voivodeship population. Polish J Surg. 2012;84(12):618-25.
  • Xiao AY, Tan MLY, Wu LM, Asrani VM, Windsor JA, Yadav D, et al. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. Lancet Gastroenterol Hepatol. 2016;1(1):45-55.
  • Andersson B, Appelgren B, Sjödin V, Ansari D, Nilsson J, Persson U, et al. Acute pancreatitis – costs for healthcare and loss of production. Scand J Gastroenterol. 2013;48(12):1459-65.
  • Bogdan J, Elsaftawy A, Kaczmarzyk J, Jabłecki J. Epidemiological characteristic of acute pancreatitis in Trzebnica district. Polish J Surg. 2012;84(2):70-5.
  • Tenner S, Baillie J, DeWitt J, Vege SS. American College of Gastroenterology guideline: management of acute pancreatitis. Am J Gastroenterol. 2013;108(9):1400-15.
  • De Waele J. IAP/APA evidence-based guidelines for the management of acute pancreatitis. Pancreatology. 2013;13(4 suppl 2):1-15.
  • Mayor S. A fifth of acute pancreatitis cases are not diagnosed promptly, inquiry warns. BMJ. 2016;354:i3746.
  • Roberts SE, Akbari A, Thorne K, Atkinson M, Evans PA. The incidence of acute pancreatitis: impact of social deprivation, alcohol consumption, seasonal and demographic factors. Aliment Pharmacol Ther. 2013;38(5):539-48.
  • Yadav D. Recent advances in the epidemiology of alcoholic pancreatitis. Curr Gastroenterol Rep. 2011;13(2):157-65.
  • Pérez-Mateo M. How we predict the etiology of acute pancreatitis. JOP. 2006;7(3):257-61.
  • Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013;144(6):1252-61.
  • Farthing M, Roberts SE, Samuel DG, Williams JG, Thorne K, Morrison-Rees S, et al. Survey of digestive health across Europe: final report. Part 1: the burden of gastrointestinal diseases and the organisation and delivery of gastroenterology services across Europe. United Eur Gastroenterol J. 2014;2(6):539-43.
  • Lee JK, Enns R. Review of idiopathic pancreatitis. World J Gastroenterol. 2007;13(47):6296-313.
  • Appelros S, Borgström A. Incidence, aetiology and mortality rate of acute pancreatitis over 10 years in a defined urban population in Sweden. Br J Surg. 1999;86(4):465-70.
  • Werner J, Feuerbach S, Uhl W, Büchler MW. Management of acute pancreatitis: from surgery to interventional intensive care. Gut. 2005;54(3):426-36.
  • Zerem E. Treatment of severe acute pancreatitis and its complications. World J Gastroenterol. 2014;20(38):1387-29.
  • Hollemans RA, van Brunschot S, Bakker OJ, Bollen TL, Timmer R, Besselink MGH, et al. Minimally invasive intervention for infected necrosis in acute pancreatitis. Expert Rev Med Devices. 2014;11(6):637-48.
  • Mauri G, Mattiuz C, Sconfienza LM, Pedicini V, Poretti D, Melchiorre F, et al. Role of interventional radiology in the management of complications after pancreatic surgery: a pictorial review. Insights Imaging. 2015;6(2):231-9.
  • Connor S, Raraty MGT, Howes N, Evans J, Ghaneh P, Sutton R, et al. Surgery in the treatment of acute pancreatitis minimal access pancreatic necrosectomy. Scand J Surg. 2005;94(2):135-42.
  • Fernández-Cruz L, Lozano-Salazar RR, Olvera C, Higueras O, López-Boado MA, Astudillo E, et al. Acute necrotizing pancreatitis: therapeutic alternatives. Cir Esp. 2006;80(2):64-71.
  • Segal D, Mortele KJ, Banks PA, Silverman SG. Acute necrotizing pancreatitis: role of CT-guided percutaneous catheter drainage. Abdom Imaging. 2007;32(3):351-61.
  • Seewald S, Ang TL, Teng KCYK, Soehendra N. EUS‐guided drainage of pancreatic pseudocysts, abscesses and infected necrosis. Dig Endosc. 2009;21:S61-5.
  • Bhatia M. Acute pancreatitis as a model of SIRS. Front Biosci. 2009;14(1):2042-50.
  • Neoptolemos JP, Raraty M, Finch M, Sutton R. Acute pancreatitis: the substantial human and financial costs. Gut. 1998;42(6):886–91.
  • Munhoz-Filho CH, Batigalia F, Funez HLX. Clinical and therapeutic correlations in patients with slight acute pancreatitis. ABCD Arq Bras Cir Dig (São Paulo). 2015;28(1):24-7.
  • Andrén Sandberg A, Borgström A. Early prediction of severity in acute pancreatitis. Is this possible? JOP. 2002;3(5):116-25.
  • Agarwal N, Pitchumoni CS, Sivaprasad A V. Evaluating tests for acute pancreatitis. Am J Gastroenterol. 1990;85(4):356-66.
  • Kim YS, Lee BS, Kim SH, Seong JK, Jeong HY, Lee HY. Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis? World J Gastroenterol. 2008;14(15):2401-5.
  • Lee W-S, Huang J-F, Chuang W-L. Outcome assessment in acute pancreatitis patients. Kaohsiung J Med Sci. 2013;29(9):469-77.
  • Sarathi Patra P, Das K, Bhattacharyya A, Ray S, Hembram J, Sanyal S, et al. Natural resolution or intervention for fluid collections in acute severe pancreatitis. Br J Surg. 2014;101(13):1721-8.
  • Manrai M, Kochhar R, Gupta V, Yadav TD, Dhaka N, Kalra N, et al. Outcome of acute pancreatic and peripancreatic collections occurring in patients with acute pancreatitis. Ann Surg. 2018;267(2):357-63.
  • Van Santvoort HC, Bakker OJ, Bollen TL, Besselink MG, Ali UA, Schrijver AM, et al. A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology. 2011;141(4):1254-63.
  • Smoczyński M, Marek I, Dubowik M, Rompa G, Kobiela J, Studniarek M, et al. Endoscopic drainage/debridement of walled-off pancreatic necrosis – single center experience of 112 cases. Pancreatology. 2014;14(2):137-42.
  • Jagielski M, Smoczyński M, Adrych K. Endoscopic treatment of walled-off pancreatic necrosis complicated with pancreaticocolonic fistula. Surg Endosc. 2018;32(3):1572-80.
  • Jagielski M, Smoczyński M, Jabłońska A, Adrych K. The Development of Endoscopic Techniques for Treatment of Walled-Off Pancreatic Necrosis: A Single-Center Experience. Gastroenterol Res Pract. 2018;2018:1-9.
  • Jagielski M, Smoczyński M, Studniarek M, Adrych K. Spontaneous regression of asymptomatic walled-off pancreatic necrosis. Arch Med Sci. 2018;14(1).
  • Jagielski M, Smoczyński M, Jabłońska A, Marek I, Dubowik M, Adrych K. The role of endoscopic ultrasonography in endoscopic debridement of walled-off pancreatic necrosis–a single center experience. Pancreatology. 2015;15(5):503-7.
  • Da Costa DW, Boerma D, Van Santvoort HC, Horvath KD, Werner J, Carter CR, et al. Staged multidisciplinary step‐up management for necrotizing pancreatitis. Br J Surg. 2014;101(1):e65–79.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.doi-10_31373_ejtcm_99570
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