Aim Ageing is a natural and unavoidable phenomenon of a global nature. With age, the phenomenon of multiple disease and occurrence of various disabilities increases. Without a doubt, it is one of numerous factors influencing the quality of life, which is a highly complex term. Comparison of the quality of life of geriatric patients staying in care and treatment institutions with elderly people living with their families or alone was the aim of the study. Material and methods The study was conducted in a group of 102 persons for the period of three months. For the purpose of the study the following tools were used: WHOQOL-BREF scale, Katz scale, Norton scale and Geriatric Depression Scale. Verification of the differences between the variables was performed with the χ2 independence test and with Mann-Whitney test. Significance level of p<0.05 was assumed. Results Persons remaining in institution (47.1%) and living in a house/apartment (49.9%) rated their quality of life at a similar level. Among the persons remaining in the long-term care institution, these were more commonly the individuals with considerable level of disability (60.4%). Persons with moderate disability (42.6%) and fully fit (44.4%) more frequently live with a family or alone. In CTI patients, a higher risk of pressure ulcers occurred and it was 64.6%. The occurrence of depression among seniors is not significantly influenced by the method and location of their residence. Conclusions The quality of life of persons remaining in long-term care facilities is very similar to the quality of life of seniors who reside with family or alone.