Own experience from the use of a substitute of an allogeneic acellular dermal matrix revitalized with in vitro cultured skin cells in clinical practice

• Authors: Wojciech Łabuś , Marek Kawecki , Justyna Glik , Mariusz Maj , Diana Kitala , Marcelina Misiuga , Agnieszka Klama-Baryła , Małgorzata Kraut , Mariusz Nowak

Abstracts

EN

As a result of the removal of cells from human allogeneic dermis, a collagen scaffold is obtained, which can be populated de novo with autologous/allogeneic skin cells and transplanted onto the area of skin loss. The optimal method for production of acellular dermal matrices (ADM) has been selected. Three female patients (a mean age of 54 years) were subjected to the transplantation of either autologous or allogeneic keratinocytes and fibroblasts into the holes of acellular dermal matrix (ADM) mesh graft. The method for burn wound treatment based on the use of a viable dermal-epidermal skin substitute (based on ADM and in vitro cultured fibroblasts and keratinocytes) may be the optimal method of burn treatment.

Keywords

EN

acellular dermal matrix ADM; burn; fibroblasts; keratinocytes; tissue engineering

• Publisher: Index Copernicus International
• Journal: Polish Journal of Surgery
• Year: 2015
• Volume: 87(10)
• Pages: 513-521

Contributors

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Wojciech Łabuś

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Marek Kawecki

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Justyna Glik

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Mariusz Maj

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Diana Kitala

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Marcelina Misiuga

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Agnieszka Klama-Baryła

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Małgorzata Kraut

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Mariusz Nowak