PL EN


Preferences help
enabled [disable] Abstract
Number of results
2017 | 89(6) | 17-22
Article title

Association between clinical stage of oral cancer and expression of immunohistochemical markers

Content
Title variants
Languages of publication
Abstracts
EN
Aim: The aim of this study is to demonstrate the possible correlation between the expression of examined protein markers - p53, EGFR, PCNA, p44/42 in the mass of the tumor and the clinical stage of disease. Material: 48 patients of the Department and Clinic of Oral and Maxillofacial Surgery, Lublin diagnosed with oral cancer. The control group consisted of 10 patients diagnosed with leukoplakia lesions in the oral cavity. The methods: Immunohistochemical analysis using the detection system DAKO K5007 Cat - Dako REAL ™ Detection System, Peroxidase DAB +, Rabbit / Mouse. Results: Based upon the statistical results, significant correlation between p53 protein and tumor staging; however, a correlation between the level of expression of EGFR, p44/42, PCNA and staging was not likewise revealed. Conclusions: Looking for oral squamous cell carcinoma markers remains an actual issue. Identification of specific markers of oral cancer could be used in screening the population, determining prognosis and response to treatment.
Year
Volume
Pages
17-22
Physical description
Dates
published
2017-12-08
References
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.ceon.element-d2173dc9-74f0-3e85-a8c3-32d59b004b3e
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.